Association of genetic variation on chromosome 9p21.3 and arterial stiffness
نویسندگان
چکیده
منابع مشابه
Association of genetic variation on chromosome 9p21.3 and arterial stiffness.
OBJECTIVES Genome wide association studies have consistently reported associations between a region on chromosome 9p21.3 and a broad range of vascular diseases, such as coronary artery disease (CAD), aortic and intracranial aneurysms and type-2 diabetes (T2D). However, clear associations with intermediate phenotypes have not been described so far. To shed light on a possible influence of this c...
متن کاملStructural and genetic bases of arterial stiffness.
Arterial stiffness has independent predictive value for cardiovascular events. We review data concerning the heritability of arterial stiffness, and propose an integrated view of the structural and genetic determinants of arterial stiffness, based on a candidate gene approach and recent studies on gene expression profile. Arterial stiffness seems to have a genetic component, which is largely in...
متن کاملAssociation of Arterial Stiffness Following Glucose Uptake and Exercise with Baseline Vitamin D Levels in Inactive Men and Women
vitamin D deficiency is associated with many cardiovascular disorders. Arterial stiffness responses also depend on nutritional and exercise. Therefore, the study aimed to investigate the relationship between arterial stiffness response after glucose uptake and exercise with baseline levels of vitamin D in inactive men and women. The present study was an analysis correlation study, and the subj...
متن کاملAssociation between Vitamin D and arterial stiffness.
V D is a type of fat-soluble pleiotropic hormone. In addition to known effects regarding calcium metabolism, numerous reports of effects on the cardiovascular system have recently been published. [1–3] Low vitamin D concentration (defined as serum 25-hydroxy vitamin D concentration either below 50 nmol/L or 20 ng/ml) can impair vascular function. Vitamin D deficiency may cause vascular inflamma...
متن کاملAssociation Between Arterial Stiffness and Atherosclerosis
14. Nakashima T, Tanikawa J. A study of human aortic distensibility withrelation to atherosclerosis and aging. Angiology. 1971;22:477–490.15. Avolio AP, Deng FQ, Li WQ, Luo YF, Huang ZD, Xing LF, MF OR.Effects of aging on arterial distensibility in populations with high and lowprevalence of hypertension: comparison between urban and rural com-munities in China. Circulati...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Internal Medicine
سال: 2009
ISSN: 0954-6820,1365-2796
DOI: 10.1111/j.1365-2796.2008.02020.x